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March 5, 2024, Paper: "The Inflation Reduction Act (IRA) of 2022 is the to US prescription drug pricing in two decades and the first expected to result in a . Although beneficial for today’s payers and patients, the magnitude of the law’s effect on future innovation is disputed. The Congressional Budget Office (CBO) that the IRA will result in a decrease of one new drug in the first decade and an additional 12 drugs over the following two decades. An industry-sponsored study of a decrease of 230 drugs in the first decade alone. With the law now well into its implementation, assumption-driven forecast models should increasingly give way to contemporary empirical evidence. If the IRA is as consequential as its and contend, evidence of its effects may already be emerging."